{"product_id":"9780367398316","title":"Hematopoietic Stem Cell Transplantation","description":"\u003cp\u003eThis book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. \n\u003cbr\u003eExamines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life.\n\u003cbr\u003eCovering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation \u003c\/p\u003e\n\n\u003cp\u003esummarizes current understanding and development of clinical allogeneic HSC transplantation \n\u003cbr\u003e \n\u003cbr\u003ediscusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation \n\u003cbr\u003e \n\u003cbr\u003econsiders various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors \n\u003cbr\u003e \n\u003cbr\u003edetails detection of bone marrow contamination by tumor cells and removal procedures \n\u003cbr\u003e \n\u003cbr\u003efocuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors \n\u003cbr\u003e \n\u003cbr\u003eexplores the effects of growth factor administration and leukapheresis on PB stem cell donors \n\u003cbr\u003e \n\u003cbr\u003eshows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use \n\u003cbr\u003e \n\u003cbr\u003ereveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells \n\u003cbr\u003e \n\u003cbr\u003eemploys automated fluorescence image cytometry to study early HSC behavior following seeding\n\u003cbr\u003eIncorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study,\u003c\/p\u003e","brand":"CRC Press","offers":[{"title":"Default Title","offer_id":50099294208248,"sku":"00000_00000_00000_00000","price":164.86,"currency_code":"AUD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0789\/8208\/6904\/files\/9780367398316-1.jpg?v=1785715920","url":"https:\/\/kinokuniya.com.au\/products\/9780367398316","provider":"Books Kinokuniya Australia","version":"1.0","type":"link"}